Brain Aging & Exercise Prescription
✔Principles of Exercise Prescription in Aging to Prevent Cognitive Decline.

KEY POINTS
Exercise has been shown a positive impact on Brain Health and Reduce the Risk of Dementia.
The Review indicates that Physical Inactivity is a Major Risk Factor for Dementia, while Exercise can Improve Brain Health.
Exercise facilitates Muscle-to-Brain Signaling, promoting Neuroplasticity and Cognitive Function in the Hippocampus.
BDNF - Brain-derived Neurotrophic Factor (BDNF) IS THE KEY Substance in the Hippocampus that initiates the cascade of Neuroplasticity and Cognitive Improvements due to Exercise.
Consistent Exercise over time can increase levels of BDNF in the Hippocampus and Improve Cognition in older adults.
Physical activity, including Aerobic Exercise and Resistance Training, can lead to structural and functional Changes in the Brain, improving Memory and Cognitive Function.
The review Highlights the importance of Prescribing Moderate-to-Vigorous Exercise to facilitate Muscle-to-Brain Signaling and reach Optimal Cognitive Benefits.
SUMMARY
The Principles of Exercise Prescription for Brain Health in Aging
Alzheimer’s Disease and related Dementias are significant challenges affecting millions globally, with projections indicating a worsening scenario. In the current absence of a cure, there is an urgent need for interventions to reduce Dementia Risk.
The most common cause of Dementia is Alzheimer's Disease, accounting for 60-80% of cases, followed by Vascular Dementia.
Dementia involves a decline in Memory, Thinking, and Reasoning skills to varying degrees, which can affect Cognitive Functions with sufficient severity to affect Daily Living and Independent Functions.
Currently, over 55 Million People Worldwide have Dementia, and without effective intervention, it is projected to double every 20 years, affecting over 150 million people by 2050. Although Exercise shows promise, specific Prescriptions to Improve Cognition are Lacking.
- This Review aims to provide a brief overview of the existing evidence and propose Guidelines for Prescribing Exercise Programs that promote or preserve Brain Health During Aging…………….CONTINUES
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